We developed a method for rapid generation of B cell receptor (BCR) monoclonal mice expressing prerearranged and chains monoallelically from your locus by CRISPR-Cas9 injection into fertilized oocytes. Benschop et al., 2001). Although mice can be generated relatively rapidly using this strategy, the truth the transgenic BCR is definitely indicated from a nonnative locus prospects… Continue reading We developed a method for rapid generation of B cell receptor