Mass spectrometry (MS) evaluation for detection of immunoglobulins (IG) of the human being IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. were purified using affinity chromatography and then digested by a combination of AspN and trypsin proteases, and peptides of interest were recognized by mass spectrometry. The level… Continue reading Mass spectrometry (MS) evaluation for detection of immunoglobulins (IG) of the