Argininosuccinate synthetase (ASS), an integral enzyme to synthesize arginine is certainly down regulated in lots of tumors including hepatocellular carcinoma (HCC). rather than in HepG2 and Huh-1 (ASS(+)) cells, and it is partly because of reduced anti-apoptotic protein X-linked inhibitor of apoptosis proteins (XIAP), myeloid leukemia cell differentiation proteins (Mcl-1) and B-cell lymphoma-2 (Bcl-2). Significantly,… Continue reading Argininosuccinate synthetase (ASS), an integral enzyme to synthesize arginine is certainly